Duration-controlled swimming exercise training induces cardiac hypertrophy in mice

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Duration-controlled swimming exercise training induces cardiac hypertrophy in mice.

Exercise training associated with robust conditioning can be useful for the study of molecular mechanisms underlying exercise-induced cardiac hypertrophy. A swimming apparatus is described to control training regimens in terms of duration, load, and frequency of exercise. Mice were submitted to 60- vs 90-min session/day, once vs twice a day, with 2 or 4% of the weight of the mouse or no workloa...

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Swimming training increases cardiac vagal activity and induces cardiac hypertrophy in rats.

The effect of swimming training (ST) on vagal and sympathetic cardiac effects was investigated in sedentary (S, N = 12) and trained (T, N = 12) male Wistar rats (200-220 g). ST consisted of 60-min swimming sessions 5 days/week for 8 weeks, with a 5% body weight load attached to the tail. The effect of the autonomic nervous system in generating training-induced resting bradycardia (RB) was exami...

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Small gene effect and exercise training-induced cardiac hypertrophy in mice: an Ace gene dosage study.

Small gene effects influence complex phenotypes in a context dependent manner. Here we evaluated whether increasing dosage of the angiotensin I converting enzyme (Ace) gene influence exercise-induced cardiac hypertrophy. Mice harboring one, two, three, and four copies of the Ace gene were assigned to sedentary (S1-4) and swimming exercise-trained (T1-4) groups (1.5 h twice daily, 5 days/wk, 4 w...

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تأثیر هشت هفته تمرین تناوبی خیلی شدید بر بیان ژن خانواده miR-29 و هایپرتروفی عضله‌ی قلبی رت‌های نر سالم

Background and Objective: In this study the effect of high intensity interval training on miR-29 expression that is expressed in the heart and in the regulation of physiological processes, including extracellular matrix and cardiac hypertrophy of healthy male rats were examined. Materials and Methods: 16 Wistar rats were divided into training (n=8) and control (n=8) groups. After one week of fa...

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Endurance Exercise Effects on Cardiac Hypertrophy in Mice

[Purpose] The purpose of this study was to investigate the effects of eight weeks of an endurance exercise training program on cardiac hypertrophy in mice. [Subjects] Male 129 SvJ/C57BL6 mice (n=12) were used. The exercised mice ran on a motor-driven treadmill five days per week for 40 minutes at a speed of 24 m/min for eight weeks. All mice were weighed once a week to monitor excessive increas...

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ژورنال

عنوان ژورنال: Brazilian Journal of Medical and Biological Research

سال: 2003

ISSN: 0100-879X

DOI: 10.1590/s0100-879x2003001200018